Repeat parts 3a) & 3b) to investigate whether the association between haemoglobin and the log odds of death is linear. Briefly comment on whether the association is linear and state the null hypothesis being tested here. (5 marks) 4. (Multivariable logistic regression models – Confounding; 14 marks) Now use univariable logistic regression to estimate the unadjusted odds ratios of death for haemoglobin and all three potential confounders (age, sex, and malaria). Then use multivariable logistic regression (including all four variables) to estimate the adjusted odds ratios. Include haemoglobin and age as categorical variables with the following groupings – age (< 3 & ≥ 3 years, with ≥ 3 years as the reference group) and haemoglobin (<9 (low), 9-14 (normal), >14 (high) g/dL, with the haemoglobin group 9- 14 g/dL set as the reference group) [Hint – use ‘gen’ and ‘replace’ commands to create new variables]. a) Present in a table two columns – the unadjusted Odds Ratios (95% Confidence Intervals) and the adjusted Odds Ratios (95% Confidence Intervals) for the association between haemoglobin, age, sex, and malaria and the odds of death. (5 marks) b) Comment on any confounding observed by considering any changes in the odds ratio of haemoglobin (categorical version) from the univariable to the multivariable logistic regression. (3 marks) c) Investigate the confounding by exploring any univariable associations (in the controls only) between haemoglobin and the potential confounders. (3 marks) d) Comment on the associations between the potential confounders and the outcome (after adjusting for the exposure of interest, haemoglobin). Together with what you found in 4c, comment on which variables are confounding the association between haemoglobin and death. (3 marks)
Delivering a high-quality product at a reasonable price is not enough anymore.
That’s why we have developed 5 beneficial guarantees that will make your experience with our service enjoyable, easy, and safe.
You have to be 100% sure of the quality of your product to give a money-back guarantee. This describes us perfectly. Make sure that this guarantee is totally transparent.
Read moreEach paper is composed from scratch, according to your instructions. It is then checked by our plagiarism-detection software. There is no gap where plagiarism could squeeze in.
Read moreThanks to our free revisions, there is no way for you to be unsatisfied. We will work on your paper until you are completely happy with the result.
Read moreYour email is safe, as we store it according to international data protection rules. Your bank details are secure, as we use only reliable payment systems.
Read moreBy sending us your money, you buy the service we provide. Check out our terms and conditions if you prefer business talks to be laid out in official language.
Read more